This plasmid contains the 2.3 kb of the 5’-flanking region of the murine Cyclooxygenase 1 (COX-1) linked to a luciferase reporter gene. Upon transfection into a murine cell line, this construct can be used to investigate COX-1 gene regulation
Description: This plasmid, which contains 2.3Kb upstream and the
mouse PGHS-1 promoter, cloned into the Promega pGLbasic
luciferase reporter plasmid. Upon transfection, this
construct can be used to investigate PGHS-1 gene
regulation.
Contents/Vial: 50 μg in 50 μL TE buffer
Storage: Stable at –20oC. Avoid repeated freeze/thaw cycles.
Reference: Kraemer, S.A., Arthur, K.A., Denison, M.S., Smith, W.L. and
DeWitt, D.A., Arch. Biochem. Biophys., 330 : 319-328 (1996)
License: Purchase of this construct includes a license for the
propagation and use of the construct that is restricted to the
single institution that purchases the product. This includes
the unrestricted use for research and investigational
purposes, modification and publication of any and all findings
obtained therefrom. The distribution of this construct,
including the bacteria or other cells containing it, to other
institutions is strictly forbidden.