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銷售商: 北京啟維益成科技有限公司試劑部 | 查看該公司所有產品 >> |
Code | mab0014 |
Product | Ganglioside-GD3 antibody |
Description | Mouse monoclonal to Ganglioside GD3 |
Type | Primary antibody |
Clonality | Monoclonal Antibody |
Form | Tissue culture supernatant |
Raised In | Mouse |
Immunogen | Ganglioside-GD3 |
Clone | 2D2 |
Isotype | IgG3 / Kappa |
Specificity | Monoclonal antibody reacts specifically with GD3 ganglioside : (NeuAc alpha 2-8NeuAc alpha 2-3Gal beta 1-4Glc beta 1-1Cer) |
Cross Reactions | This antibody cross reacts with 9-O-AcGD3 ganglioside (9OAcNeuAc alpha 2-8NeuAc alpha 2-3Gal beta 1-4Glc beta 1-1Cer) and GT1a ganglioside (NeuAc alpha 2-8NeuAc alpha 2-3Gal beta 1-4GalNAc beta 1-4(NeuAc alpha 2-3)Gal beta 1-4Glc beta 1-1Cer). |
Applications | Useful for monitoring gangliosides in ELISA, TLC and immunoblotting. |
Working Dilutions | ELISA : 1/5 to 1/50; WB : 1/5 to 1/20. Optimal dilutions/concentrations should be determined by the end user. |
Packaging | 1 ml |
Appearance | Lyophilized (glass vial). Vial must be reconstituted with 1 ml of distilled water. |
Preservative | None |
Storage Instructions | Lyophilized powder : stable for a minimum of 2 years at -20°C ; Reconstituted supernatant should not be stored more than 2 weeks at +4°C. For extended periods : store in aliquots at -20°C |
Press | 1) Zebda N and al. Deficiency of ganglioside biosynthesis in metastatic human melanoma cells: relevance of CMP-NeuAc:LacCer alpha 2-3 sialyltransferase (GM3 synthase). FEBS Letters (1995), 362(2), 161-164. 2) Portoukalian J and al. Shedding of GD2 ganglioside in patients with retinoblastoma. Int. J. Cancer (1993), 53(6), 948-951. 3) Cerato E and al. Variable region gene segments of nine monoclonal antibodies specific to disialogangliosides (GD2, GD3) and their O-acetylated derivatives. Hybridoma (1997), 16(4), 307-316. 4) Thomas C.P and al. Gangliosides protect human melanoma cells from ionizing radiation-induced clonogenic cell death. Glycoconj. J. (1996), 13(3), 377-384. |
Related Product | lab0252 ; lab0242 ; lab0235 ; lab0246 ; lab0257 ; lab0239 ; lab0250 ...; opr0002 ; opr0008 ; opr0009 |
Date_Creation | 2005-12-22 |