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79 次 Hes1/Piezo1 通路在糖皮質激素誘導的骨質疏松癥中的關鍵作用 2025-4-22
The pivotal role of the Hes1/Piezo1 pathway in the pathophysiology of glucocorticoid-induced osteoporosisKeywords: Bone biology; Bone disease; Osteoporosis; Therapeutics.糖皮質激素
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128 次 大腦通過 PGE2 骨內感受調節負重骨：踝關節骨性關節炎和疼痛的影響 2025-4-21
Brain regulates weight bearing bone through PGE2 skeletal interoception: implication of ankle osteoarthritis and painSubject terms: Bone, Pathogenesis內感受（Interoception）是一種監
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219 次 Piezo1 介導的星狀細胞活化導致小鼠壓力誘導的胰腺纖維化 2025-4-15
Piezo1-mediated stellate cell activation causes pressure-induced pancreatic fibrosis in miceKeywords: Fibrosis; Gastroenterology.慢性胰腺炎是一種胰腺組織進行性炎癥性疾病，其特征是產
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198 次 Piezo1 通道調控結膜上皮細胞 IL表達:機械應力與眼部炎癥關聯研究 2025-4-14
Mechanoreceptor Piezo1 channel-mediated interleukin expression in conjunctival epithelial cells: Linking mechanical stress to ocular inflammationKeywords: CREB; Conjunctival epithe
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133 次 糖苷內切酶H從蛋白質糖基化分析到蛋白質折疊應用 2025-4-8
糖苷內切酶H（Endoglycosidase H，Endo H）是一種特異性識別和切割N-連接寡糖的內切糖苷酶。它在糖生物學、蛋白質組學、生物制藥等領域具有廣泛的研究和應用價值。下面我將詳細介紹Endo H的研究
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306 次 骨肉瘤與巨噬細胞相互作用的IL-8經 FAK 促進瘤生長轉移 2025-4-8
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathwaySubject terms: Bone
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319 次 NETosis 驅動高血壓患者血壓升高和血管功能障礙 2025-4-7
NETosis Drives Blood Pressure Elevation and Vascular Dysfunction in HypertensionKeywords: extracellular traps; histones; hypertension; neutrophils; protein-arginine deiminase type
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275 次 微生理系統產生的剪切力可減少關節炎3D模型中TNF-α介導的軟骨損傷 2025-4-1
Microphysiological System-Generated Physiological Shear Forces Reduce TNF-α-Mediated Cartilage Damage in a 3D Model of ArthritisKeywords: TNF‐α; articular cartilage br
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326 次 牙髓干細胞調節真皮成纖維細胞的炎癥小體通路和膠原沉積 2025-3-31
Dental Pulp Stem Cells Modulate Inflammasome Pathway and Collagen Deposition of Dermal FibroblastsKeywords: dental pulp stem cells; fibroblasts; fibrosis; inflammasome; inflammatio
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156 次 Tenascin-X 介導血流誘導的 EndMT 和動脈粥樣硬化抑制 2025-3-25
Tenascin-X Mediates Flow-Induced Suppression of EndMT and AtherosclerosisKeywords: atherosclerosis; carotid arteries; endothelium; hemodynamics; inflammation; transforming growth f
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254 次 芥菜籽過敏原 Sina1 激活腸上皮細胞與樹突狀細胞 2025-3-24
Mustard seed major allergen Sin a1 activates intestinal epithelial cells and also dendritic cells that drive type 2 immune responsesKWS：Mustard seed；Sin a1；intestinal epithelial
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140 次 動脈粥樣硬化和內皮機械轉導 2025-3-17
Atherosclerosis and endothelial mechanotransduction: current knowledge and models for future researchKeywords: atherosclerosis; endothelial cell glycocalyx; mechanotransduction; sh
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294 次 HEG1 通過調節內皮細胞中KLF2/4 表達來預防動脈粥樣硬化 2025-3-17
HEG1 Protects Against Atherosclerosis by Regulating Stable Flow-Induced KLF2/4 Expression in Endothelial CellsKeywords: KLF2/4; atherosclerosis; endothelial cells; heart-of-glass 1
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219 次 WGBS揭示蛋氨酸在母胎免疫耐受和子宮內膜容受中的表觀調控機制 2025-3-11
母胎免疫耐受是指母體免疫系統對胎兒抗原的耐受，避免對胎兒產生免疫排斥反應。子宮內膜容受性是指子宮內膜接受胚胎著床的能力。子宮內膜容受性和母胎免疫耐受是成功妊娠的兩個關鍵過程。然而，
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386 次 非侵入式液體流量計用于驗證HPLC系統在不同溶劑中的性能 2025-3-10
TESTA Analytical新發表了一篇技術研究報告，證明其非侵入式液體流量計可用于驗證HPLC系統在各種不同溶劑中的性能。HPLC分離方案采用的是許多不同的溶劑，以適應不同分析物的獨有特性。確保洗脫
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301 次 JAG1-NOTCH4 機械感應驅動動脈粥樣硬化 2025-3-10
JAG1-NOTCH4 mechanosensing drives atherosclerosisKWS：JAG1-NOTCH4；mechanosensing；atherosclerosis血流產生機械剪切應力，通過改變血管內皮細胞（ECs）的生理機能，對血管功能產生深遠影響
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327 次 辣椒素借 SIRT3 抑制鐵死亡維持線粒體穩態，減輕呼吸機致肺損傷 2025-3-10
Capsaicin mitigates ventilator-induced lung injury by suppressing ferroptosis and maintaining mitochondrial redox homeostasis through SIRT3-dependent mechanismsKeywords: Capsaicin;
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36 次 motif分析工具——MEME-CHIP 2025-3-3
揭秘基因調控的鑰匙：深度解析MEME-CHIP，你的motif分析神器 你是否好奇基因是如何被精確調控的？DNA中的“密碼片段”——motif，正是轉錄因子結合的關鍵位點，它們如同基
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366 次 腫瘤相關炎性細胞因子增強了骨髓間充質基質細胞對中性粒細胞的保護 2025-3-3
Protection of neutrophils by bone marrow mesenchymal stromal cells is enhanced by tumor-associated inflammatory cytokinesKeywords: G-CSF; inflammation; mesenchymal stromal/stem cel
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331 次 機械力調節脂肪干細胞的旁分泌功能促進大鼠皮膚擴張 2025-3-3
Mechanical force regulates the paracrine functions of ADSCs to assist skin expansion in ratsKeywords: ADSC paracrine; Angiogenesis; Collagen secretion; Mechanical force; Skin expan
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