Metabolomics is the scientific study of chemical processes involving metabolites. Specifically, metabolomics is the "systematic study of the unique chemical fingerprints that specific cellular processes leave behind", the study of their small-molecule metabolite profiles. The metabolome represents the collection of all metabolites in a biological cell, tissue, organ or organism, which are the end products of cellular processes. Thus, while mRNA gene expression data and proteomic analyses do not tell the whole story of what might be happening in a cell, metabolic profiling can give an instantaneous snapshot of the physiology of that cell. One of the challenges of systems biology and functional genomics is to integrate proteomic, transcriptomic, and metabolomic information to give a more complete picture of living organisms.
1、 Service Map
Sample collection (serum, urine, biological cell …)
Extraction of metabolites
Detection (GC-MS, LC-MS, NMR)
Pretreatment of data
PCA, PLS-DA, OPLS-DA
Advance data mining (metabolism pathway analysis, association analysis)
2、 Bioinformatics Analysis
(1) Basic Vision
Part 01: The pretreatment of raw data
Part 02: PCA analysis
Part 03: PLS-DA analysis
Part 04: OPLS-DA analysis
Part 05: Target metabolism bolting
Part06: Target metabolism identification
(2) Advance Vision
Part07: Multi-component association analysis (from the same sample)
Part08: Metabolism pathway analysis
Part09: Multi-group association analysis (form different groups)
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公司介紹:上海百趣生物醫(yī)學(xué)科技有限公司(簡(jiǎn)稱(chēng)百趣生物)成立于2013年4月,是一家專(zhuān)業(yè)提供生命科學(xué)前沿研究技術(shù)應(yīng)用、咨詢(xún)及開(kāi)發(fā)的高新技術(shù)企業(yè)。百趣生物專(zhuān)注于創(chuàng)新質(zhì)譜技術(shù)在生命科學(xué)研究與醫(yī)學(xué)健康兩大領(lǐng)域的應(yīng)用,尤其在生命科學(xué)研究領(lǐng)域,公司在國(guó)內(nèi)市場(chǎng)獲得了優(yōu)秀的口碑。自成立以來(lái),百趣生物相繼被認(rèn)定為國(guó)家高新技術(shù)企業(yè)、高新技術(shù)成果轉(zhuǎn)化項(xiàng)目、上海市科技型中小企業(yè)技術(shù)創(chuàng)新資金資助項(xiàng)目,百趣實(shí)驗(yàn)室相繼取得了病原微生物實(shí)驗(yàn)室BSL-2備案、CMA認(rèn)證。公司目前已經(jīng)建立并完善的代謝組學(xué)平臺(tái),包括非靶標(biāo)代謝組、高通量靶標(biāo)代謝組、常規(guī)靶標(biāo)代謝組、脂質(zhì)組學(xué)、代謝流檢測(cè),同時(shí)建立了蛋白質(zhì)組學(xué)平臺(tái),提供靶向及非靶向蛋白組學(xué)、修飾蛋白質(zhì)組學(xué)、多肽組學(xué)等業(yè)務(wù)。
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